Daily Archive for October 25th, 2005

Cylert dropped by FDA

The U.S. Food and Drug Agency (FDA) has recommended that health-care professionals who prescribe one of the widely used drugs for treating Attention Deficit Disorder should switch patients to other comparable drugs. The FDA cited potential for liver damage in its alert about the drug, Cylert, and generic versions of it (pemoline). Cylert, will continue to be available through pharmacies and wholesalers until supplies are exhausted

The Agency has concluded that the overall risk of liver toxicity from Cylert and generic pemoline products outweighs the benefits of this drug. In May 2005, Abbott chose to stop sales and marketing of Cylert in the U.S. All generic companies have also agreed to stop sales and marketing of this product (Pemoline tablets and chewable tablets). Cylert is a central nervous system stimulant indicated for the treatment of Attention Deficit Hyperactivity Disorder (ADHD). This product is considered second line therapy for ADHD because of its association with life threatening hepatic failure

Link to the FDA statement.

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EBD persists into adulthood

Follow-up research shows that adolescents who have emotional and behavioral disorders are likely to have psychiatric problems nearly 30 years later, according to a study entitled “Continuities between Emotional and Disruptive Behavior Disorders in Adolescence and Personality Disorders in Adulthood,” by Margareth Helgeland, Ellen Kjelsberg, and Svenn Torgersen. The article is published in the American Journal of Psychiatry (2005, volume 162, pp. 1941-1947) which requires a subscription, but the abstract is available via Pub Med. Link.

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